0ur lab is specialized in the study of innate immune response. We have notably discovered novel "PRO" and "ANTI" mechanisms that regulate lung immune responses. We now aim to translate our findings toward the clinic.
Single-cell proteomics and transcriptomics capture eosinophil development and identify the role of IL-5 in their lineage transit amplification.
Jorssen J, Van Hulst G, Mollers K, Pujol J, Petrellis G, Baptista AP, Schetters S, Baron F, Caers J, Lambrecht BN, Dewals BG, Bureau F, Desmet CJ.
Immunity. 2024 May 16:S1074-7613(24)00232-2. doi: 10.1016/j.immuni.2024.04.027. PMID: 38776917.
Airway Macrophages Encompass Transcriptionally and Functionally Distinct Subsets Altered by Smoking.
Liégeois M, Bai Q, Fievez L, Pirottin D, Legrand C, Guiot J, Schleich F, Corhay JL, Louis R, Marichal T, Bureau F.
Am J Respir Cell Mol Biol. 2022 Aug;67(2):241-252. doi: 10.1165/rcmb.2021 0563OC. PMID: 35522264; PMCID: PMC9348561.
Anti-IL5 mepolizumab minimally influences residual blood eosinophils in severe asthma.
Van Hulst G, Jorssen J, Jacobs N, Henket M, Louis R, Schleich F, Bureau F, Desmet CJ.
Eur Respir J. 2022 Mar 17;59(3):2100935. doi: 10.1183/13993003.00935-2021. PMID: 34475229.
A 2-month field cohort study of SARS-CoV-2 in saliva of BNT162b2 vaccinated nursing home workers.
Saegerman C, Diep AN, Renault V, Donneau AF, Stamatakis L, Coppieters W, Michel F, Breuer C, Dandoy M, Ek O, Gourzones C, Schyns J, Goffin E, Minner F, Durkin K, Artesi M, Bours V, Bureau F*, Gillet L*.
Commun Med (Lond). 2022 Jan 10;2:1. doi: 10.1038/s43856-021-00067-3. PMID: 35603280; PMCID: PMC9053279.
*Have contributed equally
Fabrice Bureau fabrice.bureau@uliege.be
Christophe Desmet christophe.desmet@uliege.be
Nathalie Jacobs n.jacobs@uliege.ac.be
Quartier Hôpital, B34 +4
University of Liege, GIGA
4000 Liège, Belgium
+32(0)4 366 4534/2420
